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Medicine is an ever-changing science. As new research and clinical experience broaden our knowledge, changes in treatment and drug therapy are required. The authors and the publisher of this work have checked with sources believed to be reliable in their efforts to provide information that is complete and generally in accord with the standards accepted at the time of publication. However, in view of the possibility ol human error ar changes in medical sciences, neither the authors nor the publisher nor any other party who has been involved in the prepara­tion or publication of this work warrants that the information contained herein is in every respect accurate or complete, and they disclaim all responsibility for any errors or omissions or for the results obtained from use of the information contained in this work. Readers are encouraged to confirm the information contained herein with other sources. For example and in particular, readers arc advised to check the product information sheet included in rhe package of each drug they plan to administer to be certain that the information contained in this work is accurate and that changes have not been made in rhe recommended dose or in rhe contraindications for admin­istration. This recommendation is of particular importance in connection with new or infrequently used drugs.