Book description

The monograph presents current data on the clinical and molecular genetic aspects of the development of coronary heart disease in men at a working age, taking into account the etiopathogenetic risk factors for the development of the disease, in particular dyslipidemia and imbalance of the cytokine system. This monograph presents modern literary sources of the CIS countries and foreign countries. The studied literature data allowed the authors to consider some molecular genetic predisposition factors for the development of coronary heart disease in men, especially at a young age. The main etiopathogenetic factors are dyslipidemia, cytokine imbalance and its relationship with genetic markers (genotypes of pro-inflammatory and anti-inflammatory cytokines). The molecular genetic profile of unstable angina in young men, as determined by our clinical and laboratory studies, is presented in relation to its underlying etiopathogenetic risk factors.